Cell Reports: Increasing NAD+ levels can reduce muscle amyloid aggregation and improve muscle mitochondrial homeostasis.

Recently, the team of Prof. Johan Auwerx from the Federal Institute of Technology Lausanne, Switzerland published a paper in Cell Reports (a sub-Journal of Cell) entitled “NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle”. Multi-factor biological processes are characterized by the decline of many cell functions, including mitochondrial dysfunction and protein balance disorders, which ultimately affect body homeostasis. In the process of aging, amyloid aggregation can cause a variety of protein polymerization diseases, such as Alzheimer’s disease and polymyositis

NMN synthesis method

At present, there are three main methods to produce NMN: chemical synthesis method, fermentation method and enzymatic catalyzed synthesis method. Chemical synthesis method: Chemical synthesis method is the relatively simple way to produce NMN, and the cost of this method is much lower than the other two methods. Chemical synthesis method usually requires several steps, […]

Interview with NMN discoverer Sinclair: aging can be cured and you will live to 150

David Sinclair, director of Paul F. Glenn biological aging center at Harvard University and professor of medical school, is famous for his first discovery of the anti-aging effect of β – nicotinamide mononucleotide (NMN). Not long ago, David Sinclair was interviewed by Boston Magazine, the mainstream media of the United States. Sinclair firmly believed that “aging is a disease that can be cured, and he can live to 150 years old”. His practice is even more practical.The whole family (including his dog) is taking β – nicotinamide mononucleotide, which has improved significantly.

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